Human Cardiac Gene Therapy
نویسندگان
چکیده
منابع مشابه
Gene Therapy for Cardiac Arrhythmias.
UNLABELLED Morbidity and mortality caused by cardiac arrhythmias are a major issue in developed countries. Although conventional therapeutic options including pharmacological therapy, catheter ablation, and implantable devices have shown extensive advances to help reduce morbidity and mortality, a certain segment of these arrhythmias is still refractory to treatment. Therefore, gene therapy was...
متن کاملGene Therapy in Cardiac Arrhythmias
Gene therapy has progressed from a dream to a bedside reality in quite a few human diseases. From its first application in adenosine deaminase deficiency, through the years, its application has evolved to vascular angiogenesis and cardiac arrhythmias. Gene based biological pacemakers using viral vectors or mesenchymal cells tested in animal models hold much promise. Induction of pacemaker activ...
متن کاملHuman Gene Therapy
that includes the author's particular area of expertise, the excitable membranes of the visual system, is especially good. Biochemistry is a comprehensive overview of both traditional and current topics in biochemistry. It balances detail with clarity in such a way that it offers an excellent text for medical professionals at any level. Despite all of the technology available in modern medicine...
متن کامل[Human gene therapy].
Human gene therapy and its application for the treatment of human genetic disorders, such as cystic fibrosis, cancer, and other diseases, are discussed. Gene therapy is a technique in which a functioning gene is inserted into a human cell to correct a genetic error or to introduce a new function to the cell. Many methods, including retroviral vectors and non-viral vectors, have been developed f...
متن کاملHuman gene therapy.
Adenoviral vectors are being developed for oral delivery of therapeutic genes to the intestine. Initial studies in the rat using mucolytics and direct application of adenovirus encoded with the interleukin-1 receptor antagonist gene to the jejunum produced limited gene expression. The goal of this study was to determine the role of integrins in adenovirus-mediated gene delivery to the intestina...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2018
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.118.311587